Oregon welcomes the Deion Sanders show to Autzen Stadium on Saturday. The Ducks will either halt the circus in its tracks or send the unbeaten Colorado Buffaloes soaring even further up the AP rankings.

It’s a major test for Sanders and the 19th-ranked Buffs. The 10th-ranked Ducks, led by second-year coach Dan Lanning, sport one of college football’s very best offenses. Oregon is second nationally in scoring at 58 a game. It is fourth nationally in offensive efficiency, averaging 8.3 yards per play.

Colorado’s offense has been high-flying with quarterback Shedeur Sanders at the helm, but it isn’t anywhere near as efficient as the Ducks’.

And it will need to be, because Colorado’s defense has been a turnstile so far this year. The Buffs rank 109th in defensive efficiency, allowing 6 yards per play. They’re giving up 5 yards a carry on the ground (121st).

The best way to neutralize Sanders’ ability to take a game over is to simply keep him on the sideline and keep the football out of his hands. Oregon will be the best-equipped team to do so that Colorado has faced thus far.

Here’s everything you need to know for the game:

TV and Kickoff Time

Kickoff time: 12:30 p.m. PT

Location: Autzen Stadium, Eugene, Oregon

TV Network: ABC, streaming on WatchESPN

Betting odds

Line: Oregon -21

Total: 70

Money line: Oregon -900, Colorado +600

Via Bet365

Score predictions

ESPN’s FPI gives Oregon a 93.9% chance of coming away with the win.

Bill Connelly’s SP+ projects the Ducks to win 46-17.

Saturday Out West’s Jon Gold predicts a 42-37 Oregon win:

Which Colorado will show up? The one that eked out a back-and-forth thriller against TCU in Week 1? The one that dominated Nebraska at home in Week 2? The one that needed double-overtime to beat Colorado State, despite being 3-touchdown favorites?

Saturday Out West’s Derek Peterson predicts Oregon to not only win but cover the three-score spread:

I have not been impressed with Colorado’s defense or its run game. I think Oregon will be able to jump all over the Buffs early and get what will already be an amped crowd really rocking.