Colorado is a five-point favorite over the Nebraska Cornhuskers for its Week 2 home opener.

The Buffs were a 20.5-point underdog going into last Saturday’s road game against the 17th-ranked TCU Horned Frogs, but pulled off a thrilling 45-42 victory. It was Deion Sanders’ coaching debut at Colorado, and it sent the college football world buzzing.

According to early lines from Circa Sports, the over/under for Saturday’s contest against Nebraska is set at 65.5.

Nebraska opened its season with a 13-10 loss to Minnesota last Thursday. The Huskers, under first-year head coach Matt Rhule, led 10-3 early in the fourth quarter, but allowed Minnesota to score 10 points in the final 2:32 of the game to win on a walk-off field goal.

Husker quarterback Jeff Sims was intercepted three times in the loss.

Colorado’s quarterback had a much different day in his debut. Shedeur Sanders completed 38 of his 47 pass attempts for 510 yards with four touchdowns and no interceptions. It was the first 500-yard passing game by a CU quarterback in program history and shattered the previous school record held by Tyler Hansen (474 in 2011).

“We’re gonna consistently do what we do because I’m here and I ain’t going nowhere,” Sanders said after the game. “I’m about to get comfortable in a minute.”

Kickoff against the Huskers is set for 9 a.m. PT on FOX.